In complex chemical analysis and biomedical diagnostics, relying on a single spectroscopic technique often results in a "blind spot." While Near-Infrared (NIR) offers speed, it frequently lacks specificity. Raman spectroscopy provides a precise molecular fingerprint but often battles fluorescence interference. Mid-IR offers excellent structural detail but is limited by shallow penetration depths.
The Challenge: Spatial Mismatch
The traditional solution to these limitations—using multiple separate probes to measure the same sample - introduces a critical error known as Spatial Mismatch. In heterogeneous mixtures, turbulent flows, or biological tissues, measuring two different spots (even simultaneously) means your data models are not observing chemically identical portions of the analyte. This discrepancy can significantly compromise the accuracy of chemometric models.
The Solution: True Data Fusion
We invite you to join us for an educational webinar on Combi Probes, where we will explore how art photonics fuses orthogonal spectroscopic techniques into a single fiber optic probe to achieve true Data Fusion. By combining different spectral methods in one probe, it is possible to save space, reduce sample volume requirements, and most importantly, ensure simultaneous measurement at the exact same sample point.
What We Will Cover
We will discuss the engineering and real-world applications behind our three primary Combi Probe configurations:
- ATR + Fluorescence: We will examine how combining surface chemistry (ATR) with deep-tissue signals (Fluorescence) assists in differentiating biological tissues, specifically improving the detection of tumor margins where standard IR methods may miss critical data.
- NIRaman: This section will focus on merging the quantitative speed of NIR with the molecular specificity of Raman, offering a powerful solution for precise powder analysis in industrial and bio-pharma applications.
- ATR + NIR + Raman: We will demonstrate the capabilities of the "Triple Mode" probe, designed to capture three orthogonal signals from complex liquids. This allows for the monitoring of reaction kinetics with unprecedented accuracy.
The session will demonstrate how these "hybrid models" provide higher prediction accuracy than the sum of their individual parts, creating a synergistic effect for analysis.
Webinar Registration
Please choose the session that best fits your schedule to dive deep into multimodal spectroscopy.
