Rheuma Sensor - art photonics

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15 January 2025

Technical Note: ATR Crystal Choice for Fiber-Based Process Spectroscopy

By Stanislav Perevoschikov

We are pleased to announce the release of our latest technical note, “ATR Crystal Choice for Fiber-Based Process Spectroscopy.” This comprehensive guide emphasizes the importance of Attenuated Total Reflectance (ATR) and mid-IR spectroscopy for precise, real-time process monitoring across diverse industries, including chemical processing, biopharmaceuticals, and food production. The technical note provides an overview of […]

2 January 2025

3-A Hygienic Certification for NIR Transflection Probe

By Stanislav Perevoschikov

Did you know that in 2024, art photonics GmbH achieved the prestigious 3-A Hygienic Certification for our newly designed NIR Transflection Probe? This milestone underscores our commitment to delivering cutting-edge spectroscopy solutions that adhere to the highest hygienic design standards. Regulatory hurdles often complicate the adoption of in-line spectroscopy for food quality control and process […]

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8 January 2025

SPIE Photonics West 2025 | 25–30 January 2025, San Francisco, USA

By Stanislav Perevoschikov

We are pleased to announce our participation in SPIE Photonics West 2025, the leading global event for spectroscopy and photonics, taking place from January 25–30 in San Francisco. Additionally, we are excited to present at the BiOS conference on January 26, where we will showcase our latest fiber optic solutions for biomedical and process analytical […]

5 December 2024

art photonics at the 19th Herbstkolloquium Prozessanalytik 2024

By Stanislav Perevoschikov

We’re excited to announce our presence at the 19th Herbstkolloquium Prozessanalytik, taking place from December 4–6, 2024, at Merck Darmstadt. At Booth #1, we will demonstrate how the compact Bruker FTIR Alpha II, equipped with our custom-designed fiber coupler and fiber probe, can be used for remote spectroscopy and advanced process control applications. As a […]

Optische Rheuma Diagnose - Screening und Früherkennung einer Volkskrankheit (Optical rheumatism diagnosis - screening and early detection of a widespread disease)

Today, the most common cause of serious inflammatory arthritis is rheumatoid arthritis (RA).

To be able to start with the treatment of RA on time, the disease must be diagnosed at an early stage, which is not always easy.

It was demonstrated that the light absorption and scattering characteristics of human tissue may correlate with disease development, therefore optical imaging method can be used for diagnostics and monitoring of RA. Optical imaging has high sensitivity, and specificity unique in comparison to other biomedical imaging methods. Besides expensive tomographic approaches a robust procedure has become established in optical diagnostics of rheumatism: transillumination of finger joint.

The aim of the project was the development of a robust and cost-effective prototype for non-invasive diagnostics of rheumatoid arthritis based on optical imaging.

The novelty of the solution approach consists in the construction of an optical imaging system which allows a multispectral examination in a short time. The modern software for patient acquisition (database), image acquisition and image processing will be integrated to the new rheumatoid arthritis diagnostic system. The important role in diagnostics will play the optical clearing approach, which helps to increase the penetration depth of laser irradiation into the tissue.

Advantages:

combination of multi wavelength imaging with OCA method
non-invasive diagnostic tool
digital presentation of scattered light signals of finger joints and displaying a measure of inflammation, diagnostic scoring via diagnostic wizard

Working prototype

The RheumaSensor prototype consists of transparent spherical hand support, set of quickly replaceable adjustable hand holders for different hand sizes, 3-wavelength laser emitter moving around on a 2-axis robotic arm, easy to use computer controls for emitter positioning, NIR extended CCD camera with real-time image display on computer screen, automated image registration on 3 different wavelengths. Developed software allows automatized measuring procedure (positioning of laser beams, camera control, image conversation and presentation in Cartesian co-ordinates) and image analysis.

The developed prototypes are in clinical approbation stage.