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Latest News
15 July 2024
Summer Discounts - Discover our Fiber Products!

Fiber Couplers for FTIR Spectrometers Upgrade your benchtop FTIR spectrometer with our Mirror Couplers - and experience real-time process control! Transflection Fiber Probes Reflection Fiber Probes Metal-coated Fibers Metal coated fibers (Cu- and Al-) are the optimal solution for applications in high temperature, vacuum and harsh environment conditions. They are available in: Want to know […]

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17 June 2024
Fiber Probe for Simultaneous Mid-Infrared and Fluorescence Spectroscopic Analysis

We are excited to share one of our latest articles, showcasing the groundbreaking capabilities of our multispectral Combi Probe! This innovative fiber optic design enables simultaneous analysis using both mid-infrared (Mid-IR) and fluorescence spectroscopy, offering unparalleled efficiency in spectroscopic analysis. What is the Combi Probe? The Combi Probe is a versatile tool designed for the […]

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Latest Events
4 July 2024
Optica Sensing Congress 2024 | 15-19 July 2024, Toulouse, France

We are happy to announce that our R&D Manager, Alexander Novikov, will be presenting at the Optica Sensing Congress 2024 in Toulouse, France! Join and explore our cutting-edge fiber-optic solutions designed for multispectral process-control in the 0.3-16µm range. Date: July 15, 2024Presentation Time: 11:00 AM - 11:15 AM CESTLocation: Session Room Ariane 2Session Title: Process […]

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12 June 2024
Join Us at ACHEMA 2024!

We are happy to announce that art photonics will be attending ACHEMA 2024, the premier exhibition and meeting place for globally networked process industries! Our R&D Manager, Alexander Novikov, and Sales Director, Haro Fritsche, will be present, offering you an invaluable opportunity to connect with industry experts, decision-makers, and solution providers. Don’t miss the chance […]

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About Our Company
art photonics GmbH, founded in Berlin in September 1998, is one of the worldwide leaders in development and production of specialty fiber products for a broad spectrum from 300 nm to 16 µm. Unique technologies of Polycrystalline Mid InfraRed (PIR-) fibers and Metal coated Silica fibers are used for assembly of various spectroscopy probes for medical diagnostics and industrial process control, in volume production of fiber for medical and industrial lasers, for different fiber bundles, etc. Since January 2024 art photonics GmbH is a member of NYNOMIC GROUP.

Innovative “Raman – needle” fiber optic probe for tumour delineation in the oral cavity

Posted on: 
20 March 2020

Here we report the development of a new “Raman-needle” fiber probe, which was designed and manufactured as part of the RaSure project, funded by the EU “Eurostars” program.

About RaSure project:

Oral cavity cancer is a major public health issue, with annually 300.000 new cases. Surgery is the mainstay of treatment, but adequate tumour removal is not achieved in 85% of the cases. This affects survival and leads to additional treatment of patients by radiotherapy or chemotherapy. The hands and eyes of the surgeon are insufficient for tumour delineation in the oral cavity. Significant improvement is needed to improve the surgical success rate. In frames of RaSure, a fully automated Raman spectroscopic device is under development to achieve complete tumour removal in oral cancer surgeries. The product will consist of a dedicated Raman-based tissue inspection device, the operational system and disposable fiber-optic needle probes.

The consortium, which includes three companies: art photonics GmbH, RiverD International BV and Erasmus MC was tasked to develop a fully automated Raman spectroscopic device to help surgeons achieve complete tumour removal in oral cavity cancer surgeries. The device is inspecting removed tissue to check if the tumour has been removed with a sufficient boundary of healthy tissue during the surgery. If not, the device will inform the surgeon where extra tissue should be removed to achieve complete tumour removal. The role of art photonics GmbH is the development of the unique disposable Raman-needle fiber probe that can be inserted into the tissue multiple times and measure without loss of quality of the results.

The innovative needle probe is satisfied the strict requirements from clinicians: tiny diameter (less than 1 mm), biocompatible materials and robustness. The above-mentioned features allow Raman probe to be inserted into the tissue sample multiple times. The Raman needle probe prototypes were extensively tested together with consortium partners in Erasmus MD and in Charité Clinic in operational theatre. The prototypes on fresh resected human tongue samples are showed reliable performance in recognition of cancer and non-cancer samples. The differentiation between tumour (T) and normal (N) parts of tongue are clearly visible both on Raman spectra and on PCA models. The results are perfectly corresponding to the information received from surgeon.

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