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17 May 2022
The Present and Future of Process Spectroscopy –

making sure your techniques are fit for purpose Dear Friends, Dr. Slava Artyushenko - the President & CEO of art photonics GmbH will provide a presentation on "Advances in spectral analyser technology: Fibre spectroscopy tools for process Analysis" atthe first in a series of awareness sessions that will focus on different aspects of the use of process spectroscopy techniques, on Tuesday 31st, May […]

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6 April 2022
LASER WORLD OF PHOTONICS 2022 | TRADE FAIR

25th World's Leading Trade Fair for Components, Systems & Applications of photonics | April 26-29, 2022 | Messe München In the spring of 2022, Munich will once again be the hub of the international photonics industry for a few days. From April 26 to 29, the World’s leading trade fair LASER World of PHOTONICS 2022 will be […]

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28 February 2022
EPIC Online Technology Meeting on Mid-Infrared Alliance Present and Future

DON’T MISS THIS IMPORTANT EVENT! EPIC Online Technology Meeting on Mid-Infrared Alliance Present and Future Photonic developments on the Mid-IR region (2.5um-15um) have demonstrated amazing high potential for utilization in different markets such as healthcare, communications, environmental, security and industry while, every day, new exciting applications.In this meeting, the entire MidIR community will discuss how answer […]

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28 February 2022
Photonics Days Berlin Brandenburg 2021

Welcome to visit us at: Photonics Days Berlin Brandenburg 2021 Visit our booth B05. Our Team will provide you with all the information you need about our fiber products and Services. 5th Photonics Days Berlin Brandenburg – International Innovation Conference will bring the regional and International Photonics community together again – this year half online […]

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About Our Company
art photonics GmbH, founded in Berlin in September 1998, is one of the worldwide leaders in development and production of specialty fiber products for a broad spectrum from 300 nm to 16 µm. Unique technologies of Polycrystalline Mid InfraRed (PIR-) fibers and Metal coated Silica fibers are used for assembly of various spectroscopy probes for medical diagnostics and industrial process control, in volume production of fiber for medical and industrial lasers, for different fiber bundles, etc.
art photonics

Innovative “Raman – needle” fiber optic probe for tumour delineation in the oral cavity

Posted on: 
20 March 2020

Here we report the development of a new “Raman-needle” fiber probe, which was designed and manufactured as part of the RaSure project, funded by the EU “Eurostars” program.

About RaSure project:

Oral cavity cancer is a major public health issue, with annually 300.000 new cases. Surgery is the mainstay of treatment, but adequate tumour removal is not achieved in 85% of the cases. This affects survival and leads to additional treatment of patients by radiotherapy or chemotherapy. The hands and eyes of the surgeon are insufficient for tumour delineation in the oral cavity. Significant improvement is needed to improve the surgical success rate. In frames of RaSure, a fully automated Raman spectroscopic device is under development to achieve complete tumour removal in oral cancer surgeries. The product will consist of a dedicated Raman-based tissue inspection device, the operational system and disposable fiber-optic needle probes.

The consortium, which includes three companies: art photonics GmbH, RiverD International BV and Erasmus MC was tasked to develop a fully automated Raman spectroscopic device to help surgeons achieve complete tumour removal in oral cavity cancer surgeries. The device is inspecting removed tissue to check if the tumour has been removed with a sufficient boundary of healthy tissue during the surgery. If not, the device will inform the surgeon where extra tissue should be removed to achieve complete tumour removal. The role of art photonics GmbH is the development of the unique disposable Raman-needle fiber probe that can be inserted into the tissue multiple times and measure without loss of quality of the results.

The innovative needle probe is satisfied the strict requirements from clinicians: tiny diameter (less than 1 mm), biocompatible materials and robustness. The above-mentioned features allow Raman probe to be inserted into the tissue sample multiple times. The Raman needle probe prototypes were extensively tested together with consortium partners in Erasmus MD and in Charité Clinic in operational theatre. The prototypes on fresh resected human tongue samples are showed reliable performance in recognition of cancer and non-cancer samples. The differentiation between tumour (T) and normal (N) parts of tongue are clearly visible both on Raman spectra and on PCA models. The results are perfectly corresponding to the information received from surgeon.

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