Die art photonics GmbH freut sich, die Raman-Faseroptiksonde vorzustellen – eine robuste Lösung für Industrien, die präzise Echtzeit-Spektroskopie in anspruchsvollen Umgebungen erfordern. Speziell für den Einsatz in extremen Bedingungen entwickelt, bietet diese hochempfindliche, Inline-Raman-Sonde Vielseitigkeit und Zuverlässigkeit in einer Vielzahl von Anwendungen. Hauptmerkmale Anwendungsbereiche in verschiedenen Branchen Die Raman-Faseroptiksonde ist ideal für eine Vielzahl von […]
art photonics GmbH is proud to introduce the Raman Fiber Optic Probe, a robust solution for industries requiring real-time Raman spectroscopy in demanding environments. Specifically engineered for harsh settings, this high-sensitivity, in-line Raman probe offers versatility and reliability across a wide range of applications. Key Features Applications The Raman Fiber Optic Probe is ideal for […]
Are you attending the SciX Conference this week? Don’t miss the opportunity to meet our Sales Director, Haro Fritsche, at the Avantes booth #511! Haro will be presenting art photonics' novel fiber optic probes designed for process-control in-line solutions, offering valuable insights into how our technologies can support your process analytical needs. Presentation Details: Title: […]
Just a few days left until Mini-APACT 2024! We’re excited to be part of Mini-APACT 2024 as sponsors of this year’s theme: "Developments in Application of Optical Techniques for PAT." It’s a fantastic opportunity to explore the latest advancements in Process Analytical Technology (PAT) through a series of engaging talks. Don’t miss our colleague Martin […]
art photonics GmbH, founded in Berlin in September 1998, is one of the worldwide leaders in development and production of specialty fiber products for a broad spectrum from 300 nm to 16 µm. Unique technologies of Polycrystalline Mid InfraRed (PIR-) fibers and Metal coated Silica fibers are used for assembly of various spectroscopy probes for medical diagnostics and industrial process control, in volume production of fiber for medical and industrial lasers, for different fiber bundles, etc. Since January 2024 art photonics GmbH is a member of NYNOMIC GROUP.
Innovative “Raman – needle” fiber optic probe for tumour delineation in the oral cavity
Posted on:
20 March 2020
Here we report the development of a new “Raman-needle” fiber probe, which was designed and manufactured as part of the RaSure project, funded by the EU “Eurostars” program.
About RaSure project:
Oral cavity cancer is a major public health issue, with annually 300.000 new cases. Surgery is the mainstay of treatment, but adequate tumour removal is not achieved in 85% of the cases. This affects survival and leads to additional treatment of patients by radiotherapy or chemotherapy. The hands and eyes of the surgeon are insufficient for tumour delineation in the oral cavity. Significant improvement is needed to improve the surgical success rate. In frames of RaSure, a fully automated Raman spectroscopic device is under development to achieve complete tumour removal in oral cancer surgeries. The product will consist of a dedicated Raman-based tissue inspection device, the operational system and disposable fiber-optic needle probes.
The consortium, which includes three companies: art photonics GmbH, RiverD International BV and Erasmus MC was tasked to develop a fully automated Raman spectroscopic device to help surgeons achieve complete tumour removal in oral cavity cancer surgeries. The device is inspecting removed tissue to check if the tumour has been removed with a sufficient boundary of healthy tissue during the surgery. If not, the device will inform the surgeon where extra tissue should be removed to achieve complete tumour removal. The role of art photonicsGmbH is the development of the unique disposable Raman-needle fiber probe that can be inserted into the tissue multiple times and measure without loss of quality of the results.
The innovative needle probe is satisfied the strict requirements from clinicians: tiny diameter (less than 1 mm), biocompatible materials and robustness. The above-mentioned features allow Raman probe to be inserted into the tissue sample multiple times. The Raman needle probe prototypes were extensively tested together with consortium partners in Erasmus MD and in Charité Clinic in operational theatre. The prototypes on fresh resected human tongue samples are showed reliable performance in recognition of cancer and non-cancer samples. The differentiation between tumour (T) and normal (N) parts of tongue are clearly visible both on Raman spectra and on PCA models. The results are perfectly corresponding to the information received from surgeon.
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