We are delighted to announce that art photonics is proudly serving as one of the EPIC sponsors for their 20 Years Celebration. As one of the oldest members within their esteemed community of 800, we have witnessed and contributed to the growth and success of EPIC throughout the years. Join us at this remarkable event […]
art photonics announces our presence at EuroPACT 2023 in Copenhagen, as proud sponsors of this exciting event. EuroPACT 2023 is the perfect opportunity to discover industry trends, exchange knowledge, and network with professionals in the field of optical fiber technology. Visit us at Booth 15, where you can meet our esteemed CEO, Viacheslav Artyushenko, and […]
art photonics is excited to announce that our esteemed R&D Manager, Alexander Novikov, will be delivering two engaging talks at the highly anticipated IFPAC 2023 event in Bethesda, MD (Washington, DC). This prestigious gathering serves as a prime platform for process analytical chemistry enthusiasts, making it an essential event to attend. Our relentless dedication to […]
art photonics to Showcase Cutting-Edge Fiber Optic Solutions at Laser World of Photonics 2023 in Munich We are excited to announce that art photonics will be exhibiting at Laser World of Photonics 2023 in Munich, Germany. Join us from June 27th to 30th at Booth 526 in Hall A2 to explore our advanced specialty optical […]
art photonics GmbH, founded in Berlin in September 1998, is one of the worldwide leaders in development and production of specialty fiber products for a broad spectrum from 300 nm to 16 µm. Unique technologies of Polycrystalline Mid InfraRed (PIR-) fibers and Metal coated Silica fibers are used for assembly of various spectroscopy probes for medical diagnostics and industrial process control, in volume production of fiber for medical and industrial lasers, for different fiber bundles, etc.
Innovative “Raman – needle” fiber optic probe for tumour delineation in the oral cavity
20 March 2020
Here we report the development of a new “Raman-needle” fiber probe, which was designed and manufactured as part of the RaSure project, funded by the EU “Eurostars” program.
About RaSure project:
Oral cavity cancer is a major public health issue, with annually 300.000 new cases. Surgery is the mainstay of treatment, but adequate tumour removal is not achieved in 85% of the cases. This affects survival and leads to additional treatment of patients by radiotherapy or chemotherapy. The hands and eyes of the surgeon are insufficient for tumour delineation in the oral cavity. Significant improvement is needed to improve the surgical success rate. In frames of RaSure, a fully automated Raman spectroscopic device is under development to achieve complete tumour removal in oral cancer surgeries. The product will consist of a dedicated Raman-based tissue inspection device, the operational system and disposable fiber-optic needle probes.
The consortium, which includes three companies: art photonics GmbH, RiverD International BV and Erasmus MC was tasked to develop a fully automated Raman spectroscopic device to help surgeons achieve complete tumour removal in oral cavity cancer surgeries. The device is inspecting removed tissue to check if the tumour has been removed with a sufficient boundary of healthy tissue during the surgery. If not, the device will inform the surgeon where extra tissue should be removed to achieve complete tumour removal. The role of art photonicsGmbH is the development of the unique disposable Raman-needle fiber probe that can be inserted into the tissue multiple times and measure without loss of quality of the results.
The innovative needle probe is satisfied the strict requirements from clinicians: tiny diameter (less than 1 mm), biocompatible materials and robustness. The above-mentioned features allow Raman probe to be inserted into the tissue sample multiple times. The Raman needle probe prototypes were extensively tested together with consortium partners in Erasmus MD and in Charité Clinic in operational theatre. The prototypes on fresh resected human tongue samples are showed reliable performance in recognition of cancer and non-cancer samples. The differentiation between tumour (T) and normal (N) parts of tongue are clearly visible both on Raman spectra and on PCA models. The results are perfectly corresponding to the information received from surgeon.
To provide the best experiences, we use technologies like cookies to store and/or access device information. Consenting to these technologies will allow us to process data such as browsing behavior or unique IDs on this site. Not consenting or withdrawing consent, may adversely affect certain features and functions of the website.
The technical storage or access is strictly necessary for the legitimate purpose of enabling the use of a specific service explicitly requested by the subscriber or user, or for the sole purpose of carrying out the transmission of a communication over an electronic communications network.
The technical storage or access is necessary for the legitimate purpose of storing preferences that are not requested by the subscriber or user.
The technical storage or access that is used exclusively for statistical purposes.The technical storage or access that is used exclusively for anonymous statistical purposes. Without a subpoena, voluntary compliance on the part of your Internet Service Provider, or additional records from a third party, information stored or retrieved for this purpose alone cannot usually be used to identify you.
The technical storage or access is required to create user profiles to send advertising, or to track the user on a website or across several websites for similar marketing purposes.