Rheuma Sensor - art photonics

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26 February 2024

By Stanislav Perevoschikov

Welcome to the art photonics team, Andrea Teuber! We are happy to introduce our newest team member, Andrea Teuber, to the art photonics family in Ulm, Baden-Württemberg, Germany! Andrea's expertise is mainly in laser-based mid-infrared spectroscopy - with a focus on the development of advanced laser-based spectroscopy sensors for environmental analysis and life science/bioanalytical applications. […]

11 February 2024

Reflecting on Photonics West 24 & BiOS

By Stanislav Perevoschikov

We extend our profound gratitude to SPIE, the international society for optics and photonics, for organizing Photonics West 24 & BiOS. This event provided us with the invaluable opportunity to connect with new prospects, engage with our longstanding partners, and reunite with friends. As always, the conference was a showcase of spectacular innovation and collaboration, […]

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14 March 2024

APACT 2024 | 23-25 April 2024, New Brunswick, NJ, USA

By Stanislav Perevoschikov

We are excited to share that our CEO, Viacheslav Artyushenko, will be attending and presenting at APACT 2024, a key event for leaders in process monitoring, data analysis, process modeling, and control. As proud sponsors of this conference, art photonics is at the forefront of advancing Process Analytical Technology (PAT) and fostering significant progress across […]

13 March 2024

Analytica 2024 | 09–12 April, 2024, Munich, Germany

By Stanislav Perevoschikov

Join art photonics at Analytica 2024! We are happy to announce our participation in Analytica 2024, taking place from April 09 to 12, 2024, in Munich, Germany! We are more than eager to present our pioneering fiber optic solutions that define precision in remote spectroscopic measurements and are at the forefront of combining analytical methods, […]

Optische Rheuma Diagnose - Screening und Früherkennung einer Volkskrankheit (Optical rheumatism diagnosis - screening and early detection of a widespread disease)

Today, the most common cause of serious inflammatory arthritis is rheumatoid arthritis (RA).

To be able to start with the treatment of RA on time, the disease must be diagnosed at an early stage, which is not always easy.

It was demonstrated that the light absorption and scattering characteristics of human tissue may correlate with disease development, therefore optical imaging method can be used for diagnostics and monitoring of RA. Optical imaging has high sensitivity, and specificity unique in comparison to other biomedical imaging methods. Besides expensive tomographic approaches a robust procedure has become established in optical diagnostics of rheumatism: transillumination of finger joint.

The aim of the project was the development of a robust and cost-effective prototype for non-invasive diagnostics of rheumatoid arthritis based on optical imaging.

The novelty of the solution approach consists in the construction of an optical imaging system which allows a multispectral examination in a short time. The modern software for patient acquisition (database), image acquisition and image processing will be integrated to the new rheumatoid arthritis diagnostic system. The important role in diagnostics will play the optical clearing approach, which helps to increase the penetration depth of laser irradiation into the tissue.

Advantages:

combination of multi wavelength imaging with OCA method
non-invasive diagnostic tool
digital presentation of scattered light signals of finger joints and displaying a measure of inflammation, diagnostic scoring via diagnostic wizard

Working prototype

The RheumaSensor prototype consists of transparent spherical hand support, set of quickly replaceable adjustable hand holders for different hand sizes, 3-wavelength laser emitter moving around on a 2-axis robotic arm, easy to use computer controls for emitter positioning, NIR extended CCD camera with real-time image display on computer screen, automated image registration on 3 different wavelengths. Developed software allows automatized measuring procedure (positioning of laser beams, camera control, image conversation and presentation in Cartesian co-ordinates) and image analysis.

The developed prototypes are in clinical approbation stage.