PIRMAH - art photonics

Latest News

8 October 2026

Employee Spotlight: 5 Years of Dedication and Quality with Nicole

By Stanislav Perevoschikov

Behind every specialty optical fiber we manufacture and ship at art photonics, there is a dedicated team committed to getting every detail exactly right. Today, we are delighted to shine a spotlight on one of the essential people behind our production lines: Nicole, a Production Employee at art photonics. Recently marking her 5-year work anniversary […]

25 September 2026

Dual-Channel Process Monitoring: Combining NIR and Raman Spectroscopy in a Single Probe

By Stanislav Perevoschikov

During active pharmaceutical ingredient (API) crystallization and drying, comprehensive process understanding demands simultaneous insight into chemical composition and solid-state structure. Operators routinely track two distinct parameters in real time: residual solvent or moisture content, and crystal polymorphism. Historically, monitoring both attributes in situ presented a practical instrumentation bottleneck. Near-infrared (NIR) spectroscopy excels at quantifying water […]

Latest Events

13 October 2026

analytica China 2026 | 16-18 November 2026 | Shanghai New International Expo Centre (SNIEC), China

By Stanislav Perevoschikov

art photonics will be represented at analytica China 2026 in Shanghai from 16 to 18 November 2026. Together with our local distribution partner, UniqueRay Technologies Limited (Uray), we will be presenting our specialty fiber-optic solutions for inline Process Analytical Technology (PAT) and laboratory spectroscopy at Booth # E6.6920. At art photonics, we design and manufacture […]

9 September 2026

CIOE 2026 | 9-11 September 2026 | Shenzhen World Exhibition & Convention Center, China

By Stanislav Perevoschikov

art photonics GmbH is currently exhibiting at the China International Optoelectronic Exposition (CIOE) 2026 in Shenzhen. From September 9-11, we are represented at this premier industry event by our partner, UniqueRay Technologies Limited. Industry professionals are invited to visit Stand 8B16 to review our advanced portfolio of specialty fiber optic solutions. UniqueRay is showcasing our […]

PIRMAH: Photoacoustic Infrared Microscope for Automated Histopathology

Infrared microscopy is a method of choice for label free mapping of biomarkers leading to automated histopathology. However, infrared microscopy image acquisition speed is slow and offers limited spatial resolution. PIRMAH addresses these limitations by using a photoacoustic method for video rate mid-infrared (2-12μm) 2-D spectro-imaging and 3-D tomography. PIRMAH leads to commercialization of an ex-vivo microscope for automated histopathology and its miniaturization for endoscopic applications.

The overall project goal was to develop a photoacoustic infrared microscope (PIM) prototype that overcomes the limitations of conventional Fourier-transform infrared (FT-IR) microscopy, and will allow extemporaneous ex-vivo and in-vivo automated histopathology:

High speed-video-rate image acquisition speed (up to 10 MHz infrared frequency-pixel acquisition rate)
Sub-wavelength spatial resolution (down to 1 μm) to achieve a higher contrast of cellular substructures
3-D depth profiling (tomography).
Compatible with the dimension constrains of endoscopic applications

Art photonics provided the high-quality polycrystalline (PIR) and chalcogenide (CIR) glass and fibers for transmitting in the mid Infrared region.

Manufacturing methods was adapted to achieve cost effective and mass production of disposable PIM optical heads. In details, to fit the PIRMAH device, the IR fibres distal end was served as diffraction limited point source. The mechanical properties (stiffness, resistance to repeated deformation) and diameter, were met the PIRMAH fiber scanner constrains.

Project Partners